EFFICACY OF INFLIXIMAB IN REFRACTORY BEHÇET’S DISEASE-ASSOCIATED AND IDIOPATHIC POSTERIOR SEGMENT UVEITIS: A PROSPECTIVE, FOLLOW-UP STUDY OF 50 PATIENTS

Fabrizio Cantini1, Laura Niccoli1, Carlotta Nannini1, Olga Kaloudi1, Emanuele Cassarà1, Massimo Susini2, Ivo Lenzetti21Second Division of Internal Medicine, Rheumatology Unit, 2Division of Ophthalmology, Prato Hospital, Prato, ItalyPurpose: To evaluate the long-term efficacy of infliximab in patients with refractory Behçet&

This study aimed to assess two novel 5-arylideneimidazolidine-2,4-dione (hydantoin) derivatives (JH3 and JH10) demonstrating photoprotective activity using the reconstructed human skin model EpiskinTM.The skin permeability, irritation, and phototoxicity of the compounds was evaluated in vitro.Moreover, the in vitro genotoxicity and human metabolism

With technological innovations in the world of high-speed railways, railways have become an indispensable and important part of life.As a key part of the train, the safety of the wheels and axles cannot be ignored.Industry often uses non-destructive testing (NDT) methods, and because of the special structure of wheels and axles, we commonly use pha

Background: Modifications of Model Kits miRNA expression have been related to various types of cancers including hepatocellular carcinoma (HCC).miRNAs directly act as repressors of gene expression, as they reside in fragile sites, as well as cancer-related genomic regions.Notch signaling is a conserved evolutionary pathway that controls cell functi